Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921654 | 0.89 | TAAR1 (0.54) | TAAR1ADRA2AALDH1A1MEN1KMT2A | |
| SCHEMBL7910877 | 0.87 | ADRA2A (0.62) | TAAR1ADRA2AALDH1A1MEN1KMT2A | |
| SCHEMBL7918622 | 0.85 | ADRA2A (0.60) | TAAR1ADRA2AALDH1A1MEN1KMT2A | |
| SCHEMBL7913278 | 0.85 | ADRA2A (0.60) | TAAR1ADRA2AALDH1A1MEN1KMT2A | |
| SCHEMBL7924900 | 0.82 | TAAR1 (0.55) | TAAR1ADRA2AALDH1A1MEN1KMT2A | |
| SCHEMBL7923351 | 0.81 | ADRA2A (0.60) | TAAR1ADRA2A | |
| SCHEMBL7911111 | 0.78 | TAAR1 (0.65) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7918363 | 0.77 | TAAR1 (0.51) | TAAR1ADRA2AALDH1A1MEN1KMT2A | |
| SCHEMBL7919840 | 0.77 | TAAR1 (0.51) | TAAR1ADRA2AALDH1A1MEN1KMT2A | |
| SCHEMBL7918614 | 0.77 | TAAR1 (0.51) | TAAR1ADRA2AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |