⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218995 | 0.87 | CXCR4 (0.39) | — | |
| SCHEMBL6839636 | 0.80 | — | — | |
| SCHEMBL9110599 | 0.78 | LTA4H (0.31) | — | |
| SCHEMBL11817088 | 0.78 | L3MBTL1 (0.36) | — | |
| SCHEMBL27266751 | 0.77 | — | — | |
| SCHEMBL17688543 | 0.77 | — | — | |
| SCHEMBL11667201 | 0.74 | LTA4H (0.31) | — | |
| SCHEMBL26756536 | 0.74 | LTA4H (0.31) | — | |
| SCHEMBL9110587 | 0.74 | — | — | |
| SCHEMBL14156661 | 0.74 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150094315-A1 | FUSED 2-AMINOTHIAZOLE COMPOUNDS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-04-02 | — | — | US | claimed |
| US-8765747-B2 | Fused 2-aminothiazole compounds | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-07-01 | — | — | US | claimed |
| CN-103709123-A | 1, 4-dimethyl-1-alkyl piperazine ionic liquid as well as preparation method and applications thereof | UNIV ZHEJIANG | 2014-04-09 | — | — | CN | claimed |
| US-20120088766-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2012-04-12 | — | — | US | claimed |
| EP-0074559-A1 | Beta-ketoamides and pigment preparations containing these amides | BASF Aktiengesellschaft (DE) | 1983-03-23 | — | — | EP | claimed |
| WO-2023205719-A1 | KRAS G12D MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| US-11548868-B2 | Heterocyclic compounds, compositions comprising heterocyclic compound, and methods of use thereof | JS INNOPHARM (SHANGHAI) LTD. (CN) | 2023-01-10 | — | — | US | disclosed |
| CN-107249589-B | Physiologically active substance-binding block copolymer | 日本化药株式会社 | 2021-06-08 | — | — | CN | disclosed |
| US-20200339533-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF | JS INNOPHARM (SHANGHAI) LTD (CN) | 2020-10-29 | — | — | US | disclosed |
| CN-104395358-B | Comb copolymer containing ion-type binding groups | 比克化学股份有限公司 | 2016-12-07 | — | — | CN | disclosed |
| US-9505784-B2 | Fused 2-aminothiazole compounds | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160207918-A1 | SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS | VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| EP-1087981-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2001-04-04 | — | — | EP | disclosed |
| US-6180619-B1 | TREATING TUMORS OR RESTENOSIS | BIOMEASURE, INCORPORATED | 2001-01-30 | — | — | US | disclosed |
| WO-2000076521-A1 | ANTIVIRAL INDOLEOXOACETYL PIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-1999065922-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 1999-12-23 | — | — | WO | disclosed |
| WO-1997021699-A1 | PROCESS FOR MAKING 1,2-DIOXOLANES | ZENECA LIMITED (GB) | 1997-06-19 | — | — | WO | disclosed |
| US-4104174-A | HETEROCYCLIC NITROGEN HYDROCHLORIDE, ETHOXYLATED TRIDECYL ALCOHOL | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-08-01 | — | — | US | disclosed |
| US-3989460-A | CYCLIC NITROGEN COMPOUNDS AND POLYALKOXYLATED FATTY ACIDS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1976-11-02 | — | — | US | disclosed |