Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913326 | 0.88 | KDM4E (0.46) | ALDH1A1KDM4ESMN1; SMN2TP53MAPK1 | |
| SCHEMBL7913336 | 0.81 | ALDH1A1 (0.32) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL8136170 | 0.77 | SLC9A1 (0.39) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL5556431 | 0.74 | SLC9A1 (0.40) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL7916678 | 0.73 | KDM4E (0.30) | ALDH1A1KDM4ENPC1 | |
| SCHEMBL5556439 | 0.73 | SLC9A1 (0.36) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL7902834 | 0.73 | KDM4E (0.50) | ALDH1A1KDM4ESMN1; SMN2MAPK1KMT2A | |
| SCHEMBL7902827 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL7910229 | 0.71 | KDM4E (0.48) | ALDH1A1KDM4ESMN1; SMN2MAPK1KMT2A | |
| SCHEMBL7913098 | 0.71 | KDM4E (0.48) | ALDH1A1KDM4ESMN1; SMN2TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |