Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902827 | 0.89 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL5556431 | 0.81 | SLC9A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2LMNATP53 | |
| SCHEMBL7911289 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4ESMN1; SMN2LMNATP53 | |
| SCHEMBL5556439 | 0.80 | SLC9A1 (0.36) | ALDH1A1KDM4ESMN1; SMN2LMNATP53 | |
| SCHEMBL5551035 | 0.80 | HTR2A (0.39) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL5554772 | 0.77 | KDM4C (0.33) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL7912945 | 0.75 | — | — | |
| SCHEMBL8136170 | 0.75 | SLC9A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2LMNATP53 | |
| SCHEMBL11018540 | 0.73 | HTT (0.39) | ALDH1A1SMN1; SMN2LMNATP53MAPT | |
| SCHEMBL7913326 | 0.72 | KDM4E (0.46) | ALDH1A1KDM4ESMN1; SMN2TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |