Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911332 | 1.00 | SLC9A1 (0.39) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7910302 | 0.88 | SLC9A1 (0.37) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7910297 | 0.88 | SLC9A1 (0.37) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7913231 | 0.82 | SLC9A1 (0.41) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7910240 | 0.79 | ACHE (0.44) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7910243 | 0.79 | ACHE (0.44) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7903042 | 0.79 | SLC9A1 (0.39) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7912931 | 0.78 | SLC9A1 (0.59) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL927184 | 0.77 | SLC9A1 (0.61) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7916794 | 0.77 | SLC9A1 (0.61) | SLC9A1MAPTSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |