Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 10/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11186594 | 0.84 | POLB (0.44) | POLBHTTCA2GAAMAPT | |
| SCHEMBL7917819 | 0.82 | CA1 (0.49) | POLBCA2GAAMAPTKDM4E | |
| SCHEMBL11183735 | 0.81 | POLB (0.48) | POLBHTTCA2GAAMAPT | |
| SCHEMBL7284777 | 0.81 | KMT2A (0.62) | POLBHTTCA2GAAMAPT | |
| SCHEMBL7914210 | 0.81 | CA2 (0.46) | CA2GAAMAPTKDM4EMEN1 | |
| SCHEMBL7912419 | 0.80 | GAA (0.63) | CA2GAAMAPTMEN1RAB9A | |
| SCHEMBL353285 | 0.80 | CA2 (0.51) | POLBHTTCA2GAAMAPT | |
| SCHEMBL1805549 | 0.80 | MAPK1 (0.55) | POLBHTTCA2GAAMAPT | |
| SCHEMBL7141964 | 0.80 | POLB (0.49) | POLBHTTCA2GAAMAPT | |
| SCHEMBL1805547 | 0.78 | POLB (0.48) | POLBHTTCA2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |