Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.49 |
| ▸ | CA2 | P00918 | 9/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11192298 | 0.85 | CA2 (0.48) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL13545061 | 0.85 | CA1 (0.51) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL7911352 | 0.82 | POLB (0.44) | CA1CA2CA9POLBCA12 | |
| SCHEMBL7914210 | 0.82 | CA2 (0.46) | CA1CA2CA9ALDH1A1CA12 | |
| SCHEMBL1185864 | 0.81 | LMNA (0.69) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL11176923 | 0.81 | CA1 (0.53) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL2852664 | 0.81 | CA2 (0.56) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL7917776 | 0.79 | CA1 (0.59) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL27878677 | 0.79 | LMNA (0.67) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL7912419 | 0.78 | GAA (0.63) | CA1CA2CA9LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |