Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 4/20 | 0.32 |
| ▸ | ADH1C | P00326 | 3/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914853 | 0.73 | THRB (0.30) | THRBMEN1KMT2A | |
| SCHEMBL6659786 | 0.73 | THRB (0.41) | THRBMEN1KMT2A | |
| SCHEMBL9462295 | 0.73 | ADH1A (0.48) | ADH1AADH1CADH4 | |
| SCHEMBL2025297 | 0.68 | THRB (0.32) | THRBMEN1KMT2A | |
| SCHEMBL1988735 | 0.68 | THRB (0.32) | THRBMEN1KMT2A | |
| SCHEMBL2025294 | 0.68 | THRB (0.32) | THRBMEN1KMT2A | |
| SCHEMBL1353461 | 0.68 | THRB (0.32) | THRBMEN1KMT2A | |
| SCHEMBL15910655 | 0.67 | THRB (0.31) | THRBMEN1KMT2A | |
| SCHEMBL13993046 | 0.65 | THRB (0.47) | THRBMEN1KMT2A | |
| SCHEMBL113492 | 0.65 | THRB (0.47) | THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201103-B1 | MONOMERS HAVE (2-AMINOETHYL)GLYCINE BACKBONE; POLYMERASE CHAIN REACTION AMPLIFICATIONS; DETECTION OF POINT MUTATIONS; DIAGNOSIS | Nielsen, Peter E. (DK) | 2001-03-13 | — | — | US | disclosed |
| US-5977296-A | MONOMERS WITH ALIPHATIC CYCLIC STRUCTURE IN THE BACKBONE; FOR INCREASED CONFORMATION RESTRICTION LEADING TO INCREASED BINDING AFFINITY AND SPECIFICITY; FOR DETECTING POINT MUTATIONS, FOR SUPPRESSING WILD TYPE GENES IN AMPLIFICATION | NIELSEN, PETER E. (DK) | 1999-11-02 | — | — | US | disclosed |
| WO-1996020212-A2 | PEPTIDE NUCLEIC ACID INCORPORATING A CHIRAL BACKBONE | BUCHARDT, DORTE (DK) | 1996-07-04 | — | — | WO | disclosed |