Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738888 | 0.76 | BTK (0.31) | — | |
| SCHEMBL7911537 | 0.73 | THRB (0.33) | THRBMEN1KMT2A | |
| SCHEMBL5665104 | 0.71 | — | — | |
| SCHEMBL5663141 | 0.71 | ADH1A (0.32) | — | |
| SCHEMBL29255739 | 0.67 | — | — | |
| SCHEMBL9269256 | 0.67 | — | — | |
| SCHEMBL8131778 | 0.67 | — | — | |
| SCHEMBL6659786 | 0.65 | THRB (0.41) | THRBMEN1KMT2A | |
| SCHEMBL17507932 | 0.64 | HSD11B1 (0.35) | — | |
| SCHEMBL5903172 | 0.64 | HSD11B1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201103-B1 | MONOMERS HAVE (2-AMINOETHYL)GLYCINE BACKBONE; POLYMERASE CHAIN REACTION AMPLIFICATIONS; DETECTION OF POINT MUTATIONS; DIAGNOSIS | Nielsen, Peter E. (DK) | 2001-03-13 | — | — | US | disclosed |
| US-5977296-A | MONOMERS WITH ALIPHATIC CYCLIC STRUCTURE IN THE BACKBONE; FOR INCREASED CONFORMATION RESTRICTION LEADING TO INCREASED BINDING AFFINITY AND SPECIFICITY; FOR DETECTING POINT MUTATIONS, FOR SUPPRESSING WILD TYPE GENES IN AMPLIFICATION | NIELSEN, PETER E. (DK) | 1999-11-02 | — | — | US | disclosed |