SCHEMBL7911981

SCHEMBL7911981

CCCCCCCC1CCC(c2ccc(OC(F)(F)C(F)C(F)(F)F)c(Cl)c2)CC1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
PPARG P37231 3/20 0.35
PPARA Q07869 2/20 0.35
MRGPRX4 Q96LA9 1/20 0.33
RECQL P46063 1/20 0.33
MGLL Q99685 1/20 0.33
SPHK1 Q9NYA1 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2C9 P11712 1/20 0.32
S1PR1 P21453 4/20 0.32
S1PR4 O95977 1/20 0.32
S1PR5 Q9H228 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C8 P10632 1/20 0.32
S1PR3 Q99500 1/20 0.32
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913665 0.96 PPARG (0.34) GAAMAPTPPARGPPARAMRGPRX4
SCHEMBL7903494 0.96 PPARG (0.34) GAAMAPTPPARGPPARAMRGPRX4
SCHEMBL7903948 0.96 PPARG (0.36) GAAMAPTPPARGPPARAMRGPRX4
SCHEMBL7917430 0.88 MAPT (0.33) GAAMAPTRECQLMGLLSPHK1
SCHEMBL7911914 0.88 CYP2C9 (0.37) MAPTPPARGPPARAMRGPRX4RECQL
SCHEMBL8834410 0.87 GAA (0.33) GAAMAPTRECQLMGLLSPHK1
SCHEMBL7913992 0.85 GAA (0.32) GAAMAPTRECQLMGLLCYP2C9
SCHEMBL8834519 0.85 GAA (0.32) GAAMAPTRECQLMGLLCYP2C9
SCHEMBL8834634 0.84 MAPT (0.35) GAAMAPTRECQLMGLLSPHK1
SCHEMBL7917404 0.83 ALDH1A1 (0.39) GAAMAPTSPHK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed