SCHEMBL7912246

SCHEMBL7912246

C=CCC1CCC(CCCCC2CCC(CC=C)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.34
CYP1A2 P05177 1/20 0.32
NOS3 P29474 2/20 0.31
NOS1 P29475 2/20 0.31
NOS2 P35228 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7912234 1.00 SIGMAR1 (0.34) SIGMAR1CYP1A2NOS3NOS1NOS2
SCHEMBL10888358 0.89 NOS3 (0.33) NOS3NOS1NOS2
SCHEMBL10888364 0.89 NOS3 (0.33) NOS3NOS1NOS2
SCHEMBL9013868 0.89
SCHEMBL9013867 0.89
SCHEMBL10614556 0.87 CYP1A2 (0.43) SIGMAR1CYP1A2
SCHEMBL10614562 0.87 CYP1A2 (0.43) SIGMAR1CYP1A2
SCHEMBL7901794 0.86
SCHEMBL432351 0.86
SCHEMBL815076 0.86 NOS1 (0.37) NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750028-B1 Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2001-04-18 EP disclosed
US-5776367-A Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-07-07 US disclosed
EP-0750028-A2 Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-12-27 EP disclosed