Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 9/20 | 0.38 |
| ▸ | CA1 | P00915 | 7/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913936 | 0.86 | GAA (0.48) | CA2CA1CA9CA7GAA | |
| SCHEMBL7911297 | 0.79 | POLB (0.43) | POLBCA2CA1CA9CA7 | |
| SCHEMBL7913948 | 0.78 | CA2 (0.47) | CA2CA1CA9CA7GAA | |
| SCHEMBL7912319 | 0.77 | CA2 (0.46) | CA2CA1CA9CA7CA4 | |
| SCHEMBL7914152 | 0.76 | GAA (0.46) | POLBCA2CA1CA9GAA | |
| SCHEMBL7903986 | 0.74 | ADRA1A (0.60) | CA2CA1CA9GAACA4 | |
| SCHEMBL21556096 | 0.73 | POLB (0.46) | POLBCA2CA1CA9CA7 | |
| SCHEMBL6112874 | 0.73 | POLB (0.64) | POLBCA2CA1CA9CA7 | |
| SCHEMBL7914188 | 0.73 | GAA (0.48) | POLBCA2CA1CA9GAA | |
| SCHEMBL7903977 | 0.71 | ADRA1A (0.56) | CA2CA1CA9CA7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |