Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5054886 | 0.98 | KDM4E (0.45) | KDM4ENPC1ALDH1A1NFKB1RAB9A | |
| SCHEMBL29618311 | 0.95 | SPR (0.45) | KDM4ENPC1ALDH1A1NFKB1RAB9A | |
| SCHEMBL21790378 | 0.83 | SPR (0.40) | KDM4ENPC1ALDH1A1NFKB1RAB9A | |
| SCHEMBL27797588 | 0.82 | KDM4E (0.56) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3805068 | 0.78 | ALDH1A1 (0.47) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28758445 | 0.78 | HDAC3 (0.40) | NPC1NFKB1RAB9ALMNASPR | |
| SCHEMBL722849 | 0.78 | MAPK1 (0.41) | KDM4EALDH1A1MAPK1ATMCYP11B2 | |
| SCHEMBL10207558 | 0.78 | CHRM3 (0.42) | KDM4ENPC1ALDH1A1RAB9AMAPK1 | |
| SCHEMBL17675163 | 0.77 | NNMT (0.58) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL719328 | 0.77 | MAPK1 (0.40) | KDM4EALDH1A1MAPK1ATMCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |