Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 7/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835003 | 0.90 | ELANE (0.47) | KMT2AMEN1ZDHHC2FAAHELANE | |
| SCHEMBL643462 | 0.86 | KMT2A (0.63) | KMT2AKDM4EMEN1RECQLPOLB | |
| SCHEMBL9068330 | 0.85 | KMT2A (0.56) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL27525464 | 0.84 | KMT2A (0.61) | KMT2AKDM4EMEN1RECQLPOLB | |
| Bromide SCHEMBL28850559 | 0.84 | KMT2A (0.61) | KMT2AKDM4EMEN1RECQLPOLB | |
| SCHEMBL3954536 | 0.82 | ELANE (0.54) | KMT2AMEN1RECQLELANEALDH1A1 | |
| SCHEMBL8623925 | 0.82 | PRSS1 (0.56) | KMT2AKDM4EMEN1RECQLZDHHC2 | |
| SCHEMBL27537119 | 0.81 | ALDH1A1 (0.47) | KMT2AKDM4EL3MBTL1ELANEALDH1A1 | |
| SCHEMBL538653 | 0.81 | PRSS1 (0.58) | KMT2AKDM4EMEN1RECQLZDHHC2 | |
| SCHEMBL27832646 | 0.80 | LMNA (0.51) | KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962869-B2 | Process for synthesizing keto benzofuran derivatives | SANOFI (FR) | 2015-02-24 | — | — | US | disclosed |
| US-20140046078-A1 | PROCESS FOR SYNTHESIZING KETO BENZOFURAN DERIVATIVES | SANOFI (FR) | 2014-02-13 | — | — | US | disclosed |
| CN-103562193-A | Process for synthesizing keto-benzofuran derivatives | SANOFI SA | 2014-02-05 | — | — | CN | disclosed |
| CN-103562194-A | Method for synthesizing ketobenzofuran derivatives | SANOFI SA | 2014-02-05 | — | — | CN | disclosed |
| US-20140018553-A1 | PROCESS FOR SYNTHESIZING KETO-BENZOFURAN DERIVATIVES | SANOFI (FR) | 2014-01-16 | — | — | US | disclosed |
| US-6207739-B1 | Polyamide acid composition containing metal, polyimide film, flexible printed wiring board and method for producing them | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0114059-B1 | METHOD OF PREPARING A POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-06-14 | — | — | EP | disclosed |
| EP-0083690-B1 | POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE AND PROCESS FOR PREPARING POLYIMIDE FROM THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-03-12 | — | — | EP | disclosed |
| US-4515915-A | Polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-07 | — | — | US | disclosed |
| EP-0114059-A2 | Method of preparing a polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-07-25 | — | — | EP | disclosed |
| US-4454276-A | POT LIFE EXTENDING AGENT | Kanegafuchi Chkagaku Kogyo Kabushiki Kaisha (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0083690-A1 | Polyamide acid composition for preparing polyimide and process for preparing polyimide from the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046078-A1 | PROCESS FOR SYNTHESIZING KETO BENZOFURAN DERIVATIVES | CYP3A4, CYP2F1, DHPS | KMT2A 1404/4885KDM4E 93/4885MEN1 3064/4885 |
| US-20140018553-A1 | PROCESS FOR SYNTHESIZING KETO-BENZOFURAN DERIVATIVES | CYP2F1, CYP3A4, CYP2B6 | KMT2A 896/4885KDM4E 95/4885MEN1 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.