Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551100 | 0.90 | TDP1 (0.43) | ALDH1A1HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL11813454 | 0.86 | CES2 (0.42) | ALDH1A1CES2CES1 | |
| SCHEMBL7905954 | 0.83 | ALDH1A1 (0.40) | ALDH1A1CES2CES1HDAC1HDAC2 | |
| SCHEMBL10886321 | 0.83 | HDAC1 (0.50) | ALDH1A1CES2CES1HDAC1HDAC2 | |
| SCHEMBL7913152 | 0.81 | CES2 (0.38) | ALDH1A1CES2CES1HDAC1HDAC2 | |
| SCHEMBL5048589 | 0.80 | CHRM1 (0.52) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL9226685 | 0.78 | TDP1 (0.39) | ALDH1A1HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL7916149 | 0.78 | TDP1 (0.39) | ALDH1A1HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL17061404 | 0.78 | CHRM1 (0.50) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL17224638 | 0.76 | CES2 (0.50) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207739-B1 | Polyamide acid composition containing metal, polyimide film, flexible printed wiring board and method for producing them | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI (JP) | 2001-03-27 | — | — | US | disclosed |