Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401210 | 0.96 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5ALDH1A1 | |
| SCHEMBL29561956 | 0.96 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5ALDH1A1 | |
| SCHEMBL118052 | 0.96 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5ALDH1A1 | |
| SCHEMBL3202738 | 0.90 | EPHX2 (0.66) | EPHX2KMT2A | |
| SCHEMBL7921985 | 0.90 | EPHX2 (0.60) | EPHX2KMT2AMDM2RAB9ASMN1; SMN2 | |
| Acetic Acid SCHEMBL1157085 | 0.89 | EPHX2 (0.60) | EPHX2KMT2AMDM2FABP7FABP5 | |
| SCHEMBL10283985 | 0.87 | EPHX2 (0.56) | EPHX2KMT2AMDM2CASP3 | |
| SCHEMBL8366872 | 0.87 | EPHX2 (0.75) | EPHX2KMT2AFABP7FABP5ALDH1A1 | |
| SCHEMBL5189498 | 0.85 | EPHX2 (0.65) | EPHX2KMT2AFABP7FABP5RAB9A | |
| SCHEMBL22932201 | 0.85 | EPHX2 (0.65) | EPHX2KMT2AFABP7FABP5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400505-A1 | PEPTIDE-UREA DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND APPLICATION THEREOF | Bivision Pharmaceuticals, Inc (CN) | 2024-07-17 | — | — | EP | disclosed |
| US-6228985-B1 | COMPOUNDS THAT INHIBIT INTERACTION OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR WITH UROKINASE-TYPE PLASMINOGEN RECEPTOR; ANTITUMOR AGENTS; ANTIMETASTASIS AGENTS; ANTIARTHRITIC AGENTS FOR RHEUMATOID ARTHRITIS | SCHERING CORPORATION | 2001-05-08 | — | — | US | disclosed |