Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | FNTA | P49354 | 2/20 | 0.47 |
| ▸ | FNTB | P49356 | 2/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252684 | 0.92 | EPHX2 (0.67) | EPHX2KMOKMT2AMGLLNR1H4 | |
| SCHEMBL7913189 | 0.90 | EPHX2 (0.59) | EPHX2KMT2AMDM2RAB9ASMN1; SMN2 | |
| SCHEMBL3202738 | 0.89 | EPHX2 (0.66) | EPHX2KMT2AMGLL | |
| SCHEMBL118921 | 0.87 | EPHX2 (0.73) | EPHX2KMT2ANR1H4MEN1NPC1 | |
| SCHEMBL30089345 | 0.87 | EPHX2 (0.73) | EPHX2KMT2ANR1H4MEN1NPC1 | |
| SCHEMBL29400630 | 0.87 | EPHX2 (0.73) | EPHX2KMT2ANR1H4MEN1NPC1 | |
| Acetic Acid SCHEMBL1157085 | 0.86 | EPHX2 (0.60) | EPHX2KMT2AMDM2 | |
| SCHEMBL118052 | 0.86 | EPHX2 (0.63) | EPHX2KMT2A | |
| SCHEMBL29401210 | 0.86 | EPHX2 (0.63) | EPHX2KMT2A | |
| SCHEMBL29561956 | 0.86 | EPHX2 (0.63) | EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228985-B1 | COMPOUNDS THAT INHIBIT INTERACTION OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR WITH UROKINASE-TYPE PLASMINOGEN RECEPTOR; ANTITUMOR AGENTS; ANTIMETASTASIS AGENTS; ANTIARTHRITIC AGENTS FOR RHEUMATOID ARTHRITIS | SCHERING CORPORATION | 2001-05-08 | — | — | US | disclosed |