SCHEMBL29401210

SCHEMBL29401210

O=C(Nc1ccc(C(=O)O)cc1)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.63
KMT2A Q03164 2/20 0.53
FABP7 O15540 2/20 0.46
FABP5 Q01469 2/20 0.46
CASP3 P42574 2/20 0.45
ALDH1A1 P00352 1/20 0.44
PTGIR P43119 1/20 0.43
MDM4 O15151 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29561956 1.00 EPHX2 (0.63) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL118052 1.00 EPHX2 (0.63) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL7913189 0.96 EPHX2 (0.59) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL8366872 0.90 EPHX2 (0.75) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL5189498 0.88 EPHX2 (0.65) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL22932201 0.88 EPHX2 (0.65) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL15939984 0.88 EPHX2 (0.62) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL30833078 0.88 EPHX2 (0.62) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL29341843 0.88 EPHX2 (0.62) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL8239124 0.87 EPHX2 (0.60) EPHX2KMT2AFABP7FABP5MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577200-B2 High-throughput method to rapidly add chemical moieties to a small molecule library MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-03-17 US disclosed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
EP-4590670-A1 PLATFORM AND SCAFFOLD FOR FAP TARGETING AGENTS Erasmus University Rotterdam Medical Center (NL) 2025-07-30 EP disclosed
WO-2025133085-A1 SELECTIVE NPY5R AGONISTS WITH HIGH CHEMICAL AND METABOLIC STABILITY PEPHEXIA THERAPEUTICS APS (DK) 2025-06-26 WO disclosed
EP-4464341-A2 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY Technische Universität München, in Vertretung des Freistaates Bayern (DE) 2024-11-20 EP disclosed
WO-2024233346-A1 EPHA4 ANTAGONISTS AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute (US) 2024-11-14 WO disclosed
EP-4008359-B1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY UNIV MUENCHEN TECH (DE) 2024-09-11 EP disclosed
CN-114502528-B Imaging and therapeutic compositions 墨尔本大学 2024-09-06 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20220363623-A1 IMAGING AND THERAPEUTIC COMPOSITIONS THE UNIVERSITY OF MELBOURNE (AU) 2022-11-17 US disclosed
US-11497819-B2 PSMA ligands for imaging and endoradiotherapy Technische Universität München (DE) 2022-11-15 US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
EP-4031520-A1 IMAGING AND THERAPEUTIC COMPOSITIONS The University of Melbourne (AU) 2022-07-27 EP disclosed
EP-4008359-A1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY Technische Universität München (DE) 2022-06-08 EP disclosed
CN-114502528-A Imaging and therapeutic compositions 墨尔本大学 2022-05-13 CN disclosed
EP-3723815-B1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY UNIV MUENCHEN TECH (DE) 2022-04-20 EP disclosed
WO-2022060459-A1 HIGH-THROUGHPUT METHOD TO RAPIDLY ADD CHEMICAL MOIETIES TO A SMALL MOLECULE LIBRARY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-03-24 WO disclosed
US-20220089537-A1 HIGH-THROUGHPUT METHOD TO RAPIDLY ADD CHEMICAL MOIETIES TO A SMALL MOLECULE LIBRARY MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2022-03-24 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 EPHX2 4299/4885KMT2A 4690/4885FABP7 2453/4885
US-20220089537-A1 HIGH-THROUGHPUT METHOD TO RAPIDLY ADD CHEMICAL MOIETIES TO A SMALL MOLECULE LIBRARY PDE8B, ACP1, BLVRB EPHX2 913/4885KMT2A 754/4885FABP7 2403/4885
US-20220363623-A1 IMAGING AND THERAPEUTIC COMPOSITIONS CA13, CA12, CA1 EPHX2 750/4885KMT2A 1837/4885FABP7 43/4885
US-12577200-B2 High-throughput method to rapidly add chemical moieties to a small molecule library CBR3, CBR1, NR2E3 EPHX2 416/4885KMT2A 1404/4885FABP7 3316/4885
US-11497819-B2 PSMA ligands for imaging and endoradiotherapy KLK3, FOLH1, EEA1 EPHX2 1147/4885KMT2A 3352/4885FABP7 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.