SCHEMBL118052

SCHEMBL118052

O=C(Nc1ccc(C(=O)O)cc1)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.63
KMT2A Q03164 2/20 0.53
FABP7 O15540 2/20 0.46
FABP5 Q01469 2/20 0.46
CASP3 P42574 2/20 0.45
ALDH1A1 P00352 1/20 0.44
PTGIR P43119 1/20 0.43
MDM4 O15151 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29561956 1.00 EPHX2 (0.63) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL29401210 1.00 EPHX2 (0.63) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL7913189 0.96 EPHX2 (0.59) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL8366872 0.90 EPHX2 (0.75) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL5189498 0.88 EPHX2 (0.65) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL22932201 0.88 EPHX2 (0.65) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL15939984 0.88 EPHX2 (0.62) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL30833078 0.88 EPHX2 (0.62) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL29341843 0.88 EPHX2 (0.62) EPHX2KMT2AFABP7FABP5CASP3
SCHEMBL8239124 0.87 EPHX2 (0.60) EPHX2KMT2AFABP7FABP5MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4836455-B2 2011-12-14 JP claimed
EP-2281580-A2 Labeled gastrin releasing peptides (GRP) Bracco Imaging S.p.A (IT) 2011-02-09 EP claimed
EP-1585549-A4 IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING SPA (IT) 2009-07-29 EP claimed
US-7226577-B2 Gastrin releasing peptide compounds BRACCO IMAGING, S. P. A. (IT) 2007-06-05 US claimed
US-20060239923-A1 Gastrin releasing peptide compounds BRACCO IMAGING S.P.A. (IT) 2006-10-26 US claimed
EP-1585549-A2 IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS Bracco Imaging S.p.A. (IT) 2005-10-19 EP claimed
US-20040253225-A1 bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy BRACCO IMAGING S.P.A. (IT) 2004-12-16 US claimed
WO-2004065407-A2 IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2004-08-05 WO claimed
US-20040136906-A1 Gastrin releasing peptide compounds BRACCO IMAGING S.P.A. (IT) 2004-07-15 US claimed
EP-3455234-B1 SECO MACROLIDE COMPOUNDS SELVITA D O O (HR) 2026-04-01 EP disclosed
CN-119431260-A Targeting prostate specific membranes radiolabeled compounds for antigens 省卫生服务机构 2025-02-14 CN disclosed
CN-114401947-B Targeting prostate specific membranes radiolabeled compounds for antigens 省卫生服务机构 2024-11-29 CN disclosed
CN-115326937-B Solid-phase probe for capturing genotoxic impurities and use method and application thereof 山东省食品药品检验研究院 2024-06-18 CN disclosed
US-11639373-B2 Therapeutic and diagnostic agents for cancer Technische Universität München (DE) 2023-05-02 US disclosed
WO-2002024718-A1 COMPOSITIONS AND METHODS RELATING TO PROSTATE SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2002-03-28 WO disclosed
WO-2001092524-A2 MYOSIN-LIKE GENE EXPRESSED IN HUMAN HEART AND MUSCLE AEOMICA, INC. (US) 2001-12-06 WO disclosed
US-6326403-B1 CARDIOVASCULAR DISORDERS MERCK PATENT GESELLSCHAFT MIT (DE) 2001-12-04 US disclosed
CN-1309633-A Diacylhydrazine derivatives as integrin inhibitors MERCK PATENT GMBH (DE) 2001-08-22 CN disclosed
EP-0876395-A1 INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME Vertex Pharmaceuticals Incorporated (US) 1998-11-11 EP disclosed
WO-1997022618-A1 INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME VERTEX PHARMACEUTICALS INCORPORATED (US) 1997-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040253225-A1 bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy GRPR, MLNR, NPBWR1 EPHX2 3747/4885KMT2A 4045/4885FABP7 1118/4885
US-20060239923-A1 Gastrin releasing peptide compounds GRPR, GIPR, CCKBR EPHX2 2802/4885KMT2A 4189/4885FABP7 867/4885
US-20040136906-A1 Gastrin releasing peptide compounds GRPR, GIPR, MLNR EPHX2 3641/4885KMT2A 4142/4885FABP7 1103/4885
US-11639373-B2 Therapeutic and diagnostic agents for cancer CXCR4, CXCL12, CXCR3 EPHX2 1297/4885KMT2A 4704/4885FABP7 1138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.