Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8155092 | 0.89 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL944864 | 0.86 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9581855 | 0.85 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8718649 | 0.84 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| Methane SCHEMBL5839467 | 0.84 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7913244 | 0.81 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7913217 | 0.77 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8853881 | 0.77 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL2387760 | 0.76 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL613622 | 0.76 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128295-A | Hafnium-titanium-zirconium compound with trialkylaluminum and distannoxane | ENICHEM ANIC S.P.A. (IT) | 1992-07-07 | — | — | US | claimed |
| JP-2300212-A | — | — | None | — | — | JP | disclosed |
| JP-3255112-A | — | — | None | — | — | JP | disclosed |
| EP-0452840-B1 | Syndiotactic propylene copolymer, preparation of the same, and resin composition containing the same | MITSUI CHEMICALS INC (JP) | 1998-10-28 | — | — | EP | disclosed |
| JP-H03255112-A | NEW POLYMER AND POLYPROPYLENE RESIN COMPOSITION CONTAINING THE SAME | MITSUI TOATSU CHEM INC | 1991-11-14 | — | — | JP | disclosed |
| EP-0452840-A2 | Syndiotactic propylene copolymer, preparation of the same, and resin composition containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-23 | — | — | EP | disclosed |
| EP-0414202-A2 | Novel extruded polypropylene films and sheets | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-27 | — | — | EP | disclosed |
| JP-H02300212-A | PRODUCTION OF SYNDIOTACTIC POLYPROPYLENE | MITSUI TOATSU CHEM INC | 1990-12-12 | — | — | JP | disclosed |