Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581449 | 0.81 | MEN1 (0.59) | MEN1KMT2AALDH1A1BDKRB2PTGDR2 | |
| SCHEMBL4600297 | 0.80 | BDKRB2 (0.60) | MEN1KMT2AALDH1A1BDKRB2 | |
| SCHEMBL8365809 | 0.79 | KMT2A (0.61) | MEN1KMT2AALDH1A1BDKRB2PTGDR2 | |
| SCHEMBL6578362 | 0.79 | MEN1 (0.59) | MEN1KMT2AALDH1A1BDKRB2PTGDR2 | |
| SCHEMBL6580680 | 0.78 | MEN1 (0.58) | MEN1KMT2AALDH1A1BDKRB2PTGDR2 | |
| SCHEMBL6580688 | 0.78 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL6578497 | 0.77 | MEN1 (0.57) | MEN1KMT2AALDH1A1BDKRB2PTGDR2 | |
| SCHEMBL6576124 | 0.77 | MEN1 (0.57) | MEN1KMT2AALDH1A1BDKRB2PTGDR2 | |
| SCHEMBL6581282 | 0.76 | MEN1 (0.55) | MEN1KMT2AALDH1A1BDKRB2PTGDR2 | |
| SCHEMBL6576229 | 0.76 | BDKRB2 (0.54) | MEN1KMT2AALDH1A1BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211196-B1 | 8-BENZYLOXY-(TETRAHYDRO)QUINOLINE DERIVATIVES; LIVER CIRRHOSIS, ALZHEIMER*S DISEASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-04-03 | — | — | US | disclosed |