Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458786 | 0.83 | MEN1 (0.38) | MEN1TSHRKMT2ATK1 | |
| SCHEMBL3139870 | 0.80 | MEN1 (0.48) | MEN1TSHRKMT2APNPTK1 | |
| SCHEMBL7900006 | 0.79 | RAB9A (0.47) | POLB | |
| SCHEMBL7263683 | 0.76 | L3MBTL1 (0.36) | MEN1TSHRKMT2A | |
| SCHEMBL14548981 | 0.74 | MEN1 (0.42) | MEN1TSHRKMT2APNPTK1 | |
| SCHEMBL21654897 | 0.74 | RAF1 (0.43) | POLBMEN1TSHRKMT2ATK1 | |
| SCHEMBL458787 | 0.74 | CCNE2 (0.36) | MEN1TSHRKMT2A | |
| SCHEMBL24540183 | 0.74 | MEN1 (0.50) | MEN1TSHRKMT2ATK1 | |
| SCHEMBL11986875 | 0.73 | RAF1 (0.45) | POLBMEN1TSHRKMT2ATK1 | |
| SCHEMBL3132950 | 0.73 | MEN1 (0.46) | MEN1TSHRKMT2ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204326-B1 | ADDING PEPTIDE NUCLEIC ACID UNITS TO AN AMINE TERMINATED PEPTIDE NUCLEIC ACID OLIGOMER ON A SOLID PHASE SYNTHETIC RESIN; BIOSYNTHESIS | ISIS PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |
| EP-0777678-B1 | PNA COMBINATORIAL LIBRARIES AND IMPROVED METHODS OF SYNTHESIS | ISIS PHARMACEUTICALS INC (US) | 1999-10-13 | — | — | EP | disclosed |