Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.40 |
| ▸ | RPS27 | P42677 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914421 | 0.91 | ALDH1A1 (0.40) | SQORKDM4EALDH1A1MAPK8KMT2A | |
| SCHEMBL7906146 | 0.81 | SQOR (0.47) | SQORKDM4EALDH1A1MAPK8RPS27 | |
| SCHEMBL7913445 | 0.80 | KDM4E (0.41) | SQORKDM4EALDH1A1MAPK8RPS27 | |
| SCHEMBL7916403 | 0.76 | ALDH1A1 (0.40) | SQORKDM4EALDH1A1MAPK8KMT2A | |
| SCHEMBL7913465 | 0.76 | ALDH1A1 (0.40) | SQORKDM4EALDH1A1MAPK8KMT2A | |
| SCHEMBL7914416 | 0.73 | ALDH1A1 (0.40) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL2871464 | 0.72 | ALDH1A1 (0.42) | SQORKDM4EALDH1A1MAPK8RPS27 | |
| SCHEMBL7916445 | 0.72 | ALDH1A1 (0.40) | SQORKDM4EALDH1A1MAPK8RPS27 | |
| SCHEMBL7914410 | 0.71 | ALDH1A1 (0.40) | SQORKDM4EALDH1A1MAPK8KMT2A | |
| SCHEMBL20975374 | 0.67 | PDE10A (0.44) | KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297258-B1 | USEFUL AS ANTINEOPLASTIC AGENTS AND IN THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE. | AMERICAN CYANAMID COMPANY | 2001-10-02 | — | — | US | disclosed |