Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RPS27 | P42677 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914416 | 0.91 | ALDH1A1 (0.40) | KDM4EALDH1A1POLBMAPTNPSR1 | |
| SCHEMBL7906142 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1SQORPDE10APOLB | |
| SCHEMBL7913446 | 0.80 | SQOR (0.44) | KDM4EALDH1A1SQORPOLBKMT2A | |
| SCHEMBL7916401 | 0.77 | ADORA2A (0.43) | KDM4EALDH1A1POLBMAPTNPSR1 | |
| SCHEMBL7913463 | 0.76 | ALDH1A1 (0.37) | KDM4EALDH1A1SQORPOLBMAPT | |
| SCHEMBL7914421 | 0.73 | ALDH1A1 (0.40) | KDM4EALDH1A1SQORPOLBKMT2A | |
| SCHEMBL2871462 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1PDE10APOLBMAPT | |
| SCHEMBL7916437 | 0.72 | ALDH1A1 (0.38) | KDM4EALDH1A1PDE10APOLBKMT2A | |
| SCHEMBL7914406 | 0.71 | CYP1A2 (0.38) | KDM4EALDH1A1POLBKMT2AMAPT | |
| SCHEMBL29488275 | 0.71 | POLB (0.61) | KDM4EALDH1A1POLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297258-B1 | USEFUL AS ANTINEOPLASTIC AGENTS AND IN THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE. | AMERICAN CYANAMID COMPANY | 2001-10-02 | — | — | US | disclosed |