SCHEMBL7913552

SCHEMBL7913552

Clc1ccc2c(ccc3nc4ccccc4nc32)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.49
MAX P61244 1/20 0.49
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
CYP2A6 P11509 1/20 0.44
MAPT P10636 5/20 0.41
GAA P10253 3/20 0.41
ALDH1A1 P00352 3/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
NQO2 P16083 8/20 0.40
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 1/20 0.38
THRB P10828 1/20 0.38
MAPK1 P28482 1/20 0.38
BLM P54132 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5159004 0.84 MAPT (0.48) MYCMAXMAOAMAOBCYP2A6
SCHEMBL31391239 0.84 MYC (0.63) MYCMAXMAOAMAOBMAPT
SCHEMBL30713468 0.82 MAPT (0.46) MYCMAXMAOAMAOBCYP2A6
SCHEMBL1992456 0.76 CYP2A6 (0.45) MYCMAXMAOAMAOBCYP2A6
SCHEMBL4702826 0.75 HPRT1 (0.58) MYCMAXMAOACYP2A6MAPT
SCHEMBL13313381 0.73 MAPT (0.53) MYCMAXMAOAMAOBMAPT
SCHEMBL10431937 0.73 NQO2 (0.47) MAOAMAOBMAPTGAAALDH1A1
SCHEMBL4654883 0.72 MAPT (0.69) MYCMAXMAPTGAAALDH1A1
SCHEMBL23346285 0.72 MYC (0.55) MYCMAXMAOAMAOBMAPT
SCHEMBL5387138 0.72 ALDH1A1 (0.52) MAOAMAOBCYP2A6MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed