Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159004 | 0.98 | MAPT (0.48) | MAPTRAB9AGAAALDH1A1KMT2A | |
| SCHEMBL7913552 | 0.82 | MYC (0.49) | MAPTRAB9AGAAALDH1A1KMT2A | |
| SCHEMBL1992456 | 0.80 | CYP2A6 (0.45) | MAPTALDH1A1KMT2AMAOAMAOB | |
| SCHEMBL10431938 | 0.78 | NQO2 (0.56) | MAPTRAB9AGAAALDH1A1KMT2A | |
| SCHEMBL13313381 | 0.78 | MAPT (0.53) | MAPTRAB9AGAAALDH1A1KMT2A | |
| SCHEMBL10431937 | 0.78 | NQO2 (0.47) | MAPTRAB9AGAAALDH1A1KMT2A | |
| SCHEMBL4654883 | 0.77 | MAPT (0.69) | MAPTRAB9AGAAALDH1A1KMT2A | |
| SCHEMBL6304308 | 0.76 | TDP1 (0.44) | MAPTRAB9AGAAKMT2AMAOA | |
| SCHEMBL265259 | 0.76 | ALDH1A1 (0.56) | MAPTRAB9AGAAALDH1A1KMT2A | |
| SCHEMBL31487872 | 0.76 | ALDH1A1 (0.56) | MAPTRAB9AGAAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295731-A | Prodrugs of PDE10 compounds | 默沙东有限责任公司 | 2023-12-26 | — | — | CN | disclosed |