Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.70 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.67 |
| ▸ | CDK1 | P06493 | 2/20 | 0.67 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.67 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.67 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | GSK3A | P49840 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30472919 | 1.00 | ADORA2A (0.70) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL7925181 | 0.87 | ADORA2A (0.67) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL3866419 | 0.83 | ADORA2A (1.00) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL7921814 | 0.82 | ADORA2A (0.76) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL7925170 | 0.82 | ADORA2A (0.76) | ADORA2AADORA1CCNB2CDK1CCNB1 | |
| SCHEMBL27167216 | 0.81 | ADORA2A (0.70) | ADORA2AADORA1RIPK1 | |
| SCHEMBL31064954 | 0.80 | RIPK1 (1.00) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL1778522 | 0.80 | RIPK1 (1.00) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL7922300 | 0.80 | KDM4E (0.62) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL7913593 | 0.80 | ADORA2A (0.72) | ADORA2AADORA1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002348-A1 | QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2024-01-04 | — | — | US | disclosed |
| EP-4204410-A1 | QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research, an Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) (IN) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022044033-A1 | QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860)) (IN) | 2022-03-03 | — | — | WO | disclosed |
| US-6229016-B1 | PYRIDOPYRIMIDINE DERIVATIVES AS CHEMICAL INTERMEDIATES; POLYMERIZATION INHIBITION OF TUBULIN | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2001-05-08 | — | — | US | disclosed |
| US-6071930-A | FOR INHIBITION OF MITOSIS OR TUMOR GROWTH | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-06-06 | — | — | US | disclosed |
| US-5994367-A | PREVENT CELL MITOSIS; ANTICARCINOGENIC AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002348-A1 | QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | SQLE, NQO2, CYP1B1 | ADORA2A 2566/4885ADORA1 2289/4885CCNB2 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.