SCHEMBL7913621

SCHEMBL7913621

CCOCCOC1CCC(C(=O)O)CC1.FC(C(F)(F)F)C(F)(F)Oc1ccc(-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HDAC1 Q13547 5/20 0.36
HDAC2 Q92769 5/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MMP12 P39900 4/20 0.36
LIPG Q9Y5X9 1/20 0.36
HDAC3 O15379 3/20 0.34
HDAC4 P56524 3/20 0.34
HDAC7 Q8WUI4 3/20 0.34
HDAC10 Q969S8 3/20 0.34
HDAC11 Q96DB2 3/20 0.34
HDAC8 Q9BY41 3/20 0.34
HDAC6 Q9UBN7 3/20 0.34
HDAC9 Q9UKV0 3/20 0.34
HDAC5 Q9UQL6 3/20 0.34
FFAR1 O14842 2/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913553 0.91 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10HDAC1HDAC2
SCHEMBL7917443 0.91 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10HDAC1HDAC2
SCHEMBL7914029 0.86 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10HDAC1HDAC2
SCHEMBL7911766 0.86 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10HDAC1HDAC2
SCHEMBL7913826 0.84 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10LIPGKDM4E
SCHEMBL7913618 0.83 ALDH1A1 (0.42) ALDH1A1TSHRHSD17B10HDAC1HDAC2
SCHEMBL7917441 0.80 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10NPC1RAB9A
SCHEMBL7911162 0.75 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10KDM4E
SCHEMBL7913646 0.75 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10LIPGKDM4E
SCHEMBL7917586 0.73 LIPG (0.41) ALDH1A1LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed