Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL3707503 | 0.99 | S100B (0.41) | S100BMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL13741135 | 0.77 | MAPT (0.48) | S100BMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL3713566 | 0.76 | S100B (0.47) | S100BMAPTALDH1A1HTTMAPK1 | |
| Iodide SCHEMBL3711595 | 0.74 | ALDH1A1 (0.47) | MAPTALDH1A1MAPK1GAASMN1; SMN2 | |
| SCHEMBL6858562 | 0.74 | S100B (0.52) | S100BMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL26418237 | 0.73 | CNR2 (0.50) | S100BMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL26418383 | 0.72 | MAPT (0.44) | S100BMAPTALDH1A1HTTMAPK1 | |
| Iodide SCHEMBL11167246 | 0.72 | GAA (0.51) | MAPTALDH1A1HTTGAAKDM4E | |
| SCHEMBL26418379 | 0.71 | MAPT (0.45) | S100BMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL26418387 | 0.71 | MAPT (0.60) | MAPTALDH1A1HTTMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010098488-A1 | ARYL IMIDAZOLE COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |