Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527060 | 0.85 | NOTUM (0.40) | HTTSMN1; SMN2HTR6NOTUMKDM4E | |
| SCHEMBL11813906 | 0.80 | HTR6 (0.37) | SMN1; SMN2HTR6NOTUMALDH1A1CES1 | |
| SCHEMBL31147237 | 0.80 | SRD5A2 (0.43) | SMN1; SMN2HTR6NOTUMKDM4EALDH1A1 | |
| SCHEMBL335207 | 0.80 | SRD5A2 (0.43) | SMN1; SMN2HTR6NOTUMKDM4EALDH1A1 | |
| Water SCHEMBL28651054 | 0.79 | HTR6 (0.32) | HTR6ALDH1A1CES1MAOASRD5A2 | |
| SCHEMBL3614858 | 0.79 | RNASEH1 (0.36) | SMN1; SMN2HTR6NOTUMALDH1A1CES1 | |
| SCHEMBL23079026 | 0.77 | HTR6 (0.35) | SMN1; SMN2HTR6NOTUMKDM4EALDH1A1 | |
| SCHEMBL4527055 | 0.77 | HTR6 (0.35) | SMN1; SMN2HTR6KDM4EMEN1ALDH1A1 | |
| SCHEMBL30191469 | 0.77 | NOTUM (0.39) | HTR6NOTUMALDH1A1HTR2BHTR2C | |
| SCHEMBL23073778 | 0.77 | HTR6 (0.39) | HTTSMN1; SMN2HTR6NOTUMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214876-B1 | PHOSPHOLIPASE INHIBITORS | ELI LILLY AND COMPANY | 2001-04-10 | — | — | US | disclosed |