SCHEMBL335207

SCHEMBL335207

O=C(O)C1=CCc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.43
MAOA P21397 2/20 0.43
SRD5A1 P18405 1/20 0.43
MAOB P27338 1/20 0.43
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 3/20 0.40
HPGD P15428 2/20 0.40
NOTUM Q6P988 2/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 2/20 0.37
ALOX15 P16050 2/20 0.37
DAO P14920 1/20 0.37
NAPRT Q6XQN6 1/20 0.37
HTR6 P50406 1/20 0.37
CES1 P23141 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31147237 1.00 SRD5A2 (0.43) SRD5A2MAOASRD5A1MAOBALDH1A1
SCHEMBL3039377 0.88 MAOA (0.45) SRD5A2MAOASRD5A1MAOBALDH1A1
SCHEMBL11813906 0.87 HTR6 (0.37) SRD5A2MAOASRD5A1MAOBALDH1A1
SCHEMBL9254888 0.87 SRD5A2 (0.38) SRD5A2MAOASRD5A1MAOBALDH1A1
SCHEMBL3614858 0.85 RNASEH1 (0.36) SRD5A2MAOASRD5A1MAOBALDH1A1
SCHEMBL10422642 0.84 MAOA (0.39) SRD5A2MAOASRD5A1MAOBALDH1A1
SCHEMBL23079026 0.83 HTR6 (0.35) SRD5A2MAOASRD5A1MAOBALDH1A1
SCHEMBL4527060 0.83 NOTUM (0.40) MAOAALDH1A1KDM4ENOTUMSMN1; SMN2
SCHEMBL4527055 0.83 HTR6 (0.35) SRD5A2MAOASRD5A1MAOBALDH1A1
SCHEMBL15573886 0.83 NOTUM (0.39) MAOAALDH1A1NOTUMHTR6CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-103193794-B A kind of isoindolone Bing isoxazole fused ring compound and synthetic method thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2016-04-06 CN claimed
CN-103193794-A Isoindolone isoxazole fused ring compound and synthesis method thereof UNIV CHINA PHARMA 2013-07-10 CN claimed
US-6869741-B2 Electrophotographic photoreceptors with novel overcoats SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-03-22 US claimed
US-4255506-A A PHOTOSENSITIVE ORGANIC PIGMENT CONTAINING ONE OR MORE VINYL GROUPS AND RING(S) OF BENZENE, NAPHTHALENE, ANTHRACENE, AND/OR DIBENZOTHIENE; COPIERS EASTMAN KODAK COMPANY (US) 1981-03-10 US claimed
US-4165984-A UNSATURATED COMPOUND EASTMAN KODAK COMPANY (US) 1979-08-28 US claimed
EP-3359134-B1 COMPOSITIONS AND COMPOSITIONS FOR USE IN ON-DEMAND HIGH-EFFICIENCY TRIGGERABLE ANESTHESIA CHILDRENS MEDICAL CT CORP (US) 2025-04-09 EP disclosed
WO-2024190311-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, DISPLAY DEVICE AND METHOD FOR PRODUCING CURED PRODUCT 東レ株式会社 2024-09-19 WO disclosed
US-20240216341-A1 COMPOSITION FOR PREVENTING OR TREATING CHRONIC KIDNEY DISEASE, COMPRISING COMPOUND THAT INDUCES EXPRESSION OF ANTI-AGING GENE KLOTHO KLOTHO SCIENCES (KR) 2024-07-04 US disclosed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN disclosed
WO-2024085695-A1 NOVEL ALTIRATINIB DERIVATIVE, MANUFACTURING METHOD THEREFOR, AND COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF SKIN PIGMENTATION 재단법인 아산사회복지재단 2024-04-25 WO disclosed
EP-3652514-B1 TIME-TEMPERATURE INDICATOR LABEL INTRAY LTD (GB) 2023-08-23 EP disclosed
US-20230218578-A1 BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF WILMINGTON TRUST, NATIONAL ASSOCIATION 2023-07-13 US disclosed
US-5405508-A Method for regenerating tetraalkylammonium hydroxide CHLORINE ENGINEERS CORP. LTD. (JP) 1995-04-11 US disclosed
US-5354434-A Method for regenerating tetraalkylammonium hydroxide CHLORINE ENGINEERS CORP. LTD. (JP) 1994-10-11 US disclosed
US-5132313-A N-Methyl-D-Aspartate UNIVERSITY OF PITTSBURGH (US) 1992-07-21 US disclosed
US-4322487-A Composite electrically photosensitive particles for electrophoretic migration imaging process EASTMAN KODAK COMPANY (US) 1982-03-30 US disclosed
US-4255506-A A PHOTOSENSITIVE ORGANIC PIGMENT CONTAINING ONE OR MORE VINYL GROUPS AND RING(S) OF BENZENE, NAPHTHALENE, ANTHRACENE, AND/OR DIBENZOTHIENE; COPIERS EASTMAN KODAK COMPANY (US) 1981-03-10 US disclosed
US-4165984-A UNSATURATED COMPOUND EASTMAN KODAK COMPANY (US) 1979-08-28 US disclosed
US-3954850-A WITH CARBON DIOXIDE IN THE PRESENCE OF A PHENOLIC BASE TEXACO INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216341-A1 COMPOSITION FOR PREVENTING OR TREATING CHRONIC KIDNEY DISEASE, COMPRISING COMPOUND THAT INDUCES EXPRESSION OF ANTI-AGING GENE KLOTHO GLA, CTSA, FGF23 SRD5A2 2295/4885MAOA 1662/4885SRD5A1 1604/4885
US-20230218578-A1 BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF C9, C5, C1QBP SRD5A2 1770/4885MAOA 211/4885SRD5A1 1131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.