SCHEMBL7914093

SCHEMBL7914093

COCC1CCC(C2CCC(c3ccc(C(F)(F)C(F)C(F)(F)F)cc3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.33
ACACB O00763 6/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
ESR2 Q92731 2/20 0.32
CYP2C9 P11712 2/20 0.31
IDO1 P14902 1/20 0.31
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913858 0.93 DGAT1 (0.34) HTR2CACACBALDH1A1LMNAMAPT
SCHEMBL7913749 0.88 ALDH1A1 (0.33) HTR2CACACBALDH1A1LMNAMAPT
SCHEMBL7914045 0.85 ALDH1A1 (0.39) ACACBALDH1A1MAPTESR2IDO1
SCHEMBL7911110 0.84 MAOB (0.35)
SCHEMBL7903467 0.83 HTR2C (0.31) HTR2CIDO1
SCHEMBL7917509 0.82 FFAR1 (0.30)
SCHEMBL7911931 0.81 ALDH1A1 (0.42) ACACBALDH1A1MAPTESR2CYP2C9
SCHEMBL7913629 0.81 ALDH1A1 (0.33) HTR2CACACBALDH1A1LMNAMAPT
SCHEMBL7914131 0.80 ALDH1A1 (0.50) HTR2CALDH1A1LMNAMAPTESR2
SCHEMBL7914145 0.80 MAOB (0.36) HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed