Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502493 | 0.86 | RAB9A (0.50) | ERN1ALDH1A1MAPTMEN1RAB9A | |
| SCHEMBL7916672 | 0.83 | NQO2 (0.46) | ERN1ALDH1A1MAPTMEN1RAB9A | |
| SCHEMBL7916835 | 0.81 | PDE2A (0.35) | ALDH1A1MAPTMEN1RAB9AKMT2A | |
| SCHEMBL7906715 | 0.81 | MAPT (0.41) | ALDH1A1MAPTMEN1RAB9AKMT2A | |
| SCHEMBL7916817 | 0.79 | AKR1C3 (0.41) | MAPTMEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7916525 | 0.78 | AKR1C3 (0.41) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7919727 | 0.78 | HTR5A (0.53) | — | |
| SCHEMBL7915719 | 0.77 | RAB9A (0.40) | ALDH1A1MAPTMEN1RAB9AKMT2A | |
| SCHEMBL16502489 | 0.75 | LMNA (0.50) | ALDH1A1MEN1RAB9AKMT2AKDM4E | |
| SCHEMBL16502435 | 0.75 | CCNT1 (0.47) | ALDH1A1MAPTMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |