Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 11/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601156 | 0.92 | BDKRB2 (0.56) | BDKRB2MEN1KMT2APTGDR2ALDH1A1 | |
| SCHEMBL7916240 | 0.83 | BDKRB2 (0.46) | BDKRB2MEN1KMT2APTGDR2ALDH1A1 | |
| SCHEMBL7919672 | 0.82 | BDKRB2 (0.50) | BDKRB2MEN1KMT2APTGDR2ALDH1A1 | |
| SCHEMBL7913260 | 0.82 | BDKRB2 (0.44) | BDKRB2MEN1KMT2APTGDR2ALDH1A1 | |
| SCHEMBL7919667 | 0.81 | BDKRB2 (0.44) | BDKRB2MEN1KMT2APTGDR2ALDH1A1 | |
| SCHEMBL14223963 | 0.81 | BDKRB2 (0.54) | BDKRB2MEN1KMT2APTGDR2ALDH1A1 | |
| SCHEMBL4600159 | 0.81 | BDKRB2 (0.54) | BDKRB2MEN1KMT2APTGDR2ALDH1A1 | |
| SCHEMBL7914190 | 0.80 | BDKRB2 (0.50) | BDKRB2 | |
| SCHEMBL7915766 | 0.80 | BDKRB2 (0.42) | BDKRB2MEN1KMT2APTGDR2ALDH1A1 | |
| SCHEMBL4600928 | 0.76 | MEN1 (0.61) | BDKRB2MEN1KMT2APTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211196-B1 | 8-BENZYLOXY-(TETRAHYDRO)QUINOLINE DERIVATIVES; LIVER CIRRHOSIS, ALZHEIMER*S DISEASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-04-03 | — | — | US | disclosed |