Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915766 | 0.92 | BDKRB2 (0.42) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7919672 | 0.90 | BDKRB2 (0.50) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7913260 | 0.89 | BDKRB2 (0.44) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7919667 | 0.88 | BDKRB2 (0.44) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7914178 | 0.83 | BDKRB2 (0.48) | BDKRB2MEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL7914190 | 0.80 | BDKRB2 (0.50) | BDKRB2 | |
| SCHEMBL6580622 | 0.79 | BDKRB2 (0.55) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8367539 | 0.75 | GAA (0.49) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6578362 | 0.75 | MEN1 (0.59) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6580640 | 0.74 | BDKRB2 (0.42) | BDKRB2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211196-B1 | 8-BENZYLOXY-(TETRAHYDRO)QUINOLINE DERIVATIVES; LIVER CIRRHOSIS, ALZHEIMER*S DISEASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-04-03 | — | — | US | disclosed |