Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916240 | 0.90 | BDKRB2 (0.46) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7913260 | 0.88 | BDKRB2 (0.44) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7919667 | 0.87 | BDKRB2 (0.44) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7915766 | 0.85 | BDKRB2 (0.42) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7914190 | 0.83 | BDKRB2 (0.50) | BDKRB2 | |
| SCHEMBL7914178 | 0.82 | BDKRB2 (0.48) | BDKRB2MEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL4600378 | 0.82 | BDKRB2 (0.63) | BDKRB2MEN1KMT2A | |
| SCHEMBL6578830 | 0.78 | BDKRB2 (0.60) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6580680 | 0.75 | MEN1 (0.58) | BDKRB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6576080 | 0.75 | BDKRB2 (0.42) | BDKRB2KDM4EALDH1A1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211196-B1 | 8-BENZYLOXY-(TETRAHYDRO)QUINOLINE DERIVATIVES; LIVER CIRRHOSIS, ALZHEIMER*S DISEASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-04-03 | — | — | US | disclosed |