Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 11/20 | 0.37 |
| ▸ | CA1 | P00915 | 10/20 | 0.37 |
| ▸ | CA9 | Q16790 | 8/20 | 0.37 |
| ▸ | CA12 | O43570 | 7/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917803 | 0.86 | CA2 (0.41) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7904035 | 0.84 | CA2 (0.41) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7903979 | 0.83 | GAA (0.43) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7914247 | 0.77 | POLB (0.46) | POLBHTTCA2CA1CA9 | |
| SCHEMBL15077326 | 0.73 | HTT (0.50) | POLBHTTCA2CA1CA9 | |
| SCHEMBL7137336 | 0.70 | HTT (0.48) | POLBHTTCA2CA1CA9 | |
| SCHEMBL7913958 | 0.69 | CA1 (0.41) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7911297 | 0.69 | POLB (0.43) | POLBHTTCA2CA1CA9 | |
| SCHEMBL7914221 | 0.68 | KMT2A (0.40) | CA2CA1CA9CA12MAPT | |
| SCHEMBL207236 | 0.68 | CA2 (0.53) | POLBHTTCA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |