Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.41 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 5/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917803 | 0.84 | CA2 (0.41) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7914249 | 0.84 | POLB (0.38) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7903979 | 0.82 | GAA (0.43) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7904032 | 0.77 | ADRA2C (0.62) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7911341 | 0.76 | ADRA2C (0.56) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7141496 | 0.71 | CA2 (0.49) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7912319 | 0.69 | CA2 (0.46) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7913958 | 0.69 | CA1 (0.41) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7914221 | 0.67 | KMT2A (0.40) | CA2CA1CA9CA12CA4 | |
| SCHEMBL301718 | 0.66 | CA2 (0.69) | CA2CA1CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |