Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913958 | 0.86 | CA1 (0.41) | GAAPTGS2PTGS1CA1CA2 | |
| SCHEMBL7914221 | 0.84 | KMT2A (0.40) | GAAPTGS2PTGS1CA1CA2 | |
| SCHEMBL7917803 | 0.83 | CA2 (0.41) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL7914249 | 0.83 | POLB (0.38) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL7904035 | 0.82 | CA2 (0.41) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL7914223 | 0.81 | CA1 (0.39) | GAAPTGS2PTGS1CA1CA2 | |
| SCHEMBL7903986 | 0.80 | ADRA1A (0.60) | GAAPTGS2PTGS1CA1CA2 | |
| SCHEMBL7903977 | 0.80 | ADRA1A (0.56) | GAAPTGS2PTGS1CA1CA2 | |
| SCHEMBL9092422 | 0.76 | TSHR (0.58) | GAAPTGS2PTGS1CA1CA2 | |
| SCHEMBL7139259 | 0.74 | GAA (0.49) | GAAPTGS2PTGS1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |