Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963910 | 0.86 | L3MBTL1 (0.81) | L3MBTL1MAOBNR4A2PTPN1BCHE | |
| SCHEMBL6963905 | 0.86 | L3MBTL1 (0.73) | L3MBTL1BCHEABCB1NPC1RAB9A | |
| SCHEMBL7901142 | 0.83 | NR4A2 (0.74) | MAOBNR4A2PTPN1MRGPRX4MEN1 | |
| SCHEMBL1515775 | 0.81 | MEN1 (0.61) | L3MBTL1MRGPRX4NPC1RAB9AMEN1 | |
| SCHEMBL9455078 | 0.78 | ABCB1 (0.63) | L3MBTL1MAOBBCHEABCB1PARP14 | |
| SCHEMBL7914560 | 0.78 | MAOB (0.63) | L3MBTL1MAOBNR4A2PTPN1MEN1 | |
| SCHEMBL6857028 | 0.77 | L3MBTL1 (0.62) | L3MBTL1BCHEABCB1NPC1RAB9A | |
| SCHEMBL8800682 | 0.76 | NR4A2 (0.55) | L3MBTL1MAOBNR4A2PTPN1MRGPRX4 | |
| SCHEMBL13462916 | 0.76 | ABCB1 (0.64) | MAOBBCHEABCB1PARP14PARP10 | |
| SCHEMBL11639201 | 0.75 | ERCC5 (0.62) | L3MBTL1MAOBNR4A2PTPN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |