Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27879283 | 1.00 | HIF1A (0.50) | — | |
| Piperazine SCHEMBL28328748 | 0.96 | HIF1A (0.46) | — | |
| Pyrrolidine SCHEMBL2463793 | 0.85 | — | — | |
| Piperazine SCHEMBL6685072 | 0.85 | HIF1A (0.43) | — | |
| Piperazine SCHEMBL4260232 | 0.85 | HIF1A (0.43) | — | |
| Piperazine SCHEMBL27557138 | 0.82 | — | — | |
| Propane SCHEMBL3971658 | 0.82 | HIF1A (0.60) | — | |
| Piperidine SCHEMBL3005686 | 0.82 | — | — | |
| Piperidine SCHEMBL11775250 | 0.82 | ALDH1A1 (0.60) | — | |
| Piperidine SCHEMBL27896621 | 0.82 | ALDH1A1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4293063-B1 | ECONOMICAL EPOXY RESIN MATERIAL FOR EPOXY ASPHALT WITH LOW TEMPERATURE RESISTANCE AND HIGH FLEXIBILITY AS WELL AS PREPARATION METHOD THEREOF | UNIV SOUTHEAST (CN) | 2025-05-14 | — | — | EP | claimed |
| CN-113480713-A | Preparation method of polyurea quantum dot fluorescent microspheres | 上海交通大学 | 2021-10-08 | — | — | CN | claimed |
| CN-104768720-A | Wood board and production method thereof | KNAUF INSULATION LTD | 2015-07-08 | — | — | CN | claimed |
| EP-4045603-B1 | INTUMESCENT COATING COMPOSITIONS EFFECTIVE AT LOW TEMPERATURES | SWIMC LLC (US) | 2026-01-28 | — | — | EP | disclosed |
| EP-4293063-B1 | ECONOMICAL EPOXY RESIN MATERIAL FOR EPOXY ASPHALT WITH LOW TEMPERATURE RESISTANCE AND HIGH FLEXIBILITY AS WELL AS PREPARATION METHOD THEREOF | UNIV SOUTHEAST (CN) | 2025-05-14 | — | — | EP | disclosed |
| CN-114450354-B | Low temperature effective intumescent coating composition | SWIMC有限公司 | 2024-08-09 | — | — | CN | disclosed |
| US-11884842-B2 | Intumescent coating compositions effective at low temperatures | SWIMC, LLC (US) | 2024-01-30 | — | — | US | disclosed |
| US-20230174800-A1 | INTUMESCENT COATING COMPOSITIONS EFFECTIVE AT LOW TEMPERATURES | SWIMC LLC (US) | 2023-06-08 | — | — | US | disclosed |
| CN-113480713-B | Preparation method of polyurea quantum dot fluorescent microspheres | 上海交通大学 | 2023-01-24 | — | — | CN | disclosed |
| US-11525059-B2 | Intumescent coating compositions effective at low temperatures | SWIMC, LLC (US) | 2022-12-13 | — | — | US | disclosed |
| EP-3763842-B1 | COMPOSITE MATERIAL MADE OF GOLD | RICHEMONT INT SA (CH) | 2022-09-07 | — | — | EP | disclosed |
| CN-1362436-A | Aqueous polyurethane dispersing liquid as adhesive and paint and its prepn | DUAN YOULU (CN) | 2002-08-07 | — | — | CN | disclosed |
| US-6344458-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | AMERICAN HOME PRODUCTS CORPORATION | 2002-02-05 | — | — | US | disclosed |
| US-6344458-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | AMERICAN HOME PRODUCTS CORPORATION | 2002-02-05 | — | — | US | disclosed |
| EP-1140882-A1 | PIPERAZINE ETHYLAMIDE DERIVATIVES WITH 5-HT1A RECEPTOR ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035892-A1 | PIPERAZINE ETHYLAMIDE DERIVATIVES WITH 5-HT1A RECEPTOR ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-22 | — | — | WO | disclosed |
| EP-0510102-A4 | A LIQUID SPRAYABLE EPOXY COMPOSITION AND METHOD | — | 1992-12-30 | — | — | EP | disclosed |
| EP-0510102-A1 | A LIQUID SPRAYABLE EPOXY COMPOSITION AND METHOD | ZIEBART INTERNAITONAL CORPORATION (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5084521-A | Curing an epoxy resin on a truck bed | ZIEBART INTERNATIONAL CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| WO-1991010706-A1 | A LIQUID SPRAYABLE EPOXY COMPOSITION AND METHOD | ZIEBART INTERNATIONAL CORPORATION (US) | 1991-07-25 | — | — | WO | disclosed |