Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15509453 | 0.89 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL8249221 | 0.89 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL15509451 | 0.89 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL15509452 | 0.89 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL7914476 | 0.89 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL12023496 | 0.87 | CYP3A4 (0.38) | CTSBCTSS | |
| SCHEMBL13502624 | 0.87 | CTSB (0.39) | CTSBCTSS | |
| SCHEMBL11976283 | 0.86 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL13082504 | 0.86 | CTSB (0.42) | CTSBCTSS | |
| SCHEMBL11976284 | 0.86 | CTSB (0.42) | CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9623022-B2 | Macrocyclic inhibitors of hepatitis C virus | JANSSEN SCIENCES IRELAND UC (IE) | 2017-04-18 | — | — | US | disclosed |
| US-20100041728-A1 | HCV INHIBITING MACROCYCLIC PHENYLCARBAMATES | MEDIVIR AB | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041728-A1 | HCV INHIBITING MACROCYCLIC PHENYLCARBAMATES | COPB1, HAVCR2, NOD1 | CTSB 372/4885CTSS 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.