Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638501 | 0.86 | MAOB (0.57) | MAOBNR4A2NPC1RAB9ACCNB2 | |
| SCHEMBL2087954 | 0.85 | MAOB (0.71) | MAOBNR4A2NPC1RAB9ACCNB2 | |
| SCHEMBL955386 | 0.84 | MAOB (0.52) | MAOBNR4A2NPC1RAB9ACCNB2 | |
| SCHEMBL7914560 | 0.79 | MAOB (0.63) | MAOBNR4A2PTPN1NR4A1NR4A3 | |
| SCHEMBL9559962 | 0.78 | HPGD (0.54) | NPC1RAB9AKDM4ELMNAMAPT | |
| SCHEMBL28610084 | 0.78 | MEN1 (0.57) | MAOBNR4A2NPC1RAB9ACCNB2 | |
| Hydrochloric Acid SCHEMBL27218697 | 0.77 | HPGD (0.52) | NPC1RAB9AKDM4ELMNAMAPT | |
| SCHEMBL16886114 | 0.76 | CCNB2 (0.57) | MAOBNR4A2NPC1RAB9ACCNB2 | |
| SCHEMBL6088674 | 0.76 | SLC26A4 (0.63) | MAOBNR4A2NPC1RAB9ACCNB2 | |
| SCHEMBL19291686 | 0.76 | CCNB2 (0.53) | MAOBCCNB2CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1674097-B1 | Compounds effecting glucokinase | ASTRAZENECA AB (SE) | 2008-06-11 | — | — | EP | disclosed |