Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513728 | 0.83 | NAALAD2 (0.43) | NAALAD2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21052347 | 0.79 | CYP1A2 (0.48) | NAALAD2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19805240 | 0.79 | GABRP (0.48) | NAALAD2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7918002 | 0.77 | TSHR (0.42) | NAALAD2CYP1A2ALDH1A1MEN1THRB | |
| SCHEMBL27715972 | 0.77 | NAALAD2 (0.39) | NAALAD2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1752128 | 0.76 | NAALAD2 (0.42) | NAALAD2GABRPGABRDGABRA1GABRB1 | |
| Succinic Acid SCHEMBL28832688 | 0.75 | LMNA (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL20702101 | 0.75 | HMGCR (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11647058 | 0.74 | CYP1A2 (0.42) | NAALAD2GABRPGABRDGABRA1GABRB1 | |
| Propylene Glycol SCHEMBL9720403 | 0.74 | ACACB (0.44) | NAALAD2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056738-A1 | ACID LABILE PRODRUGS | Eilat, Eran (IL) | 2000-12-06 | — | — | EP | claimed |
| WO-1999037634-A1 | ACID LABILE PRODRUGS | EILAT ERAN (IL) | 1999-07-29 | — | — | WO | claimed |
| EP-1095147-A2 | POLYKETIDES, THEIR PREPARATION, AND MATERIALS FOR USE THEREIN | Biotica Technology Limited (GB) | 2001-05-02 | — | — | EP | disclosed |
| EP-1056738-A1 | ACID LABILE PRODRUGS | Eilat, Eran (IL) | 2000-12-06 | — | — | EP | disclosed |
| US-6030997-A | Acid labile prodrugs | PRODRUG, LTD. (IL) | 2000-02-29 | — | — | US | disclosed |
| WO-2000001827-A2 | POLYKETIDES, THEIR PREPARATION, AND MATERIALS FOR USE THEREIN | BIOTICA TECHNOLOGY LIMITED (GB) | 2000-01-13 | — | — | WO | disclosed |
| WO-1999037634-A1 | ACID LABILE PRODRUGS | EILAT ERAN (IL) | 1999-07-29 | — | — | WO | disclosed |
| EP-0910633-A2 | POLYKETIDES AND THEIR SYNTHESIS | Biotica Technology Limited (GB) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998001546-A2 | POLYKETIDES AND THEIR SYNTHESIS | BIOTICA TECHNOLOGY LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |