Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | MAX | P61244 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661828 | 0.88 | TACR1 (0.39) | MYCMAXMEN1MAPTKMT2A | |
| SCHEMBL7908502 | 0.83 | PLA2G1B (0.37) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL7656137 | 0.82 | MAPT (0.47) | MYCMAXMEN1MAPTKMT2A | |
| SCHEMBL7915018 | 0.79 | LMNA (0.48) | MEN1MAPTKMT2AHPGDALDH1A1 | |
| SCHEMBL7651952 | 0.78 | KMT2A (0.49) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL7981937 | 0.78 | MAOA (0.54) | MEN1MAPTKMT2AHPGDALDH1A1 | |
| SCHEMBL7639607 | 0.78 | TRPV1 (0.46) | — | |
| SCHEMBL7644918 | 0.78 | QPCT (0.45) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL7656269 | 0.78 | MYC (0.54) | MYCMAXMEN1MAPTKMT2A | |
| SCHEMBL7638276 | 0.75 | MEN1 (0.50) | MEN1MAPTKMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |