Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905397 | 0.84 | ALDH1A1 (0.59) | HPGDALDH1A1GAAPOLBMAPT | |
| SCHEMBL7905411 | 0.84 | KMT2A (0.58) | MAOAMAOBHPGDALDH1A1GAA | |
| SCHEMBL7639607 | 0.83 | TRPV1 (0.46) | — | |
| SCHEMBL7644918 | 0.80 | QPCT (0.45) | MAOAMAOBALDH1A1GAAPOLB | |
| SCHEMBL7638276 | 0.80 | MEN1 (0.50) | ALOX12HPGDALDH1A1GAAMAPT | |
| SCHEMBL7979005 | 0.79 | ALDH1A1 (0.55) | MAOAMAOBHPGDALDH1A1GAA | |
| SCHEMBL7914787 | 0.78 | MYC (0.48) | ALOX12HPGDALDH1A1GAAMAPT | |
| SCHEMBL7646586 | 0.78 | MAPT (0.50) | ALOX12ALDH1A1GAAPOLBMAPT | |
| SCHEMBL7908201 | 0.78 | SMN1; SMN2 (0.47) | ALOX12HPGDALDH1A1GAAMAPT | |
| SCHEMBL7641142 | 0.75 | NPC1 (0.58) | ALOX12HPGDALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201013-B1 | INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) INHIBITOR; SIDE EFFECT REDUCTION, NON-DRUG RESISTANT | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-13 | — | — | US | disclosed |