Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PDE1A | P54750 | 1/20 | 0.52 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915059 | 0.92 | NPSR1 (0.52) | EGFRKDRRETNPSR1MAPT | |
| SCHEMBL7912095 | 0.92 | MAPT (0.62) | EGFRKDRRETNPSR1MAPT | |
| SCHEMBL7914903 | 0.91 | ABCG2 (0.53) | EGFRKDRRETNPSR1MAPT | |
| SCHEMBL7913392 | 0.86 | ABCG2 (0.58) | EGFRKDRMAPTKDM4EALDH1A1 | |
| SCHEMBL7912315 | 0.84 | NPSR1 (0.56) | KDRNPSR1MAPTKDM4EALDH1A1 | |
| SCHEMBL7914641 | 0.82 | MAPT (0.64) | KDRNPSR1MAPTKDM4EALDH1A1 | |
| SCHEMBL7918597 | 0.82 | RXFP1 (0.57) | EGFRKDRNPSR1MAPTKDM4E | |
| SCHEMBL7918598 | 0.82 | EGFR (0.47) | EGFRKDRRETNPSR1MAPT | |
| SCHEMBL7913393 | 0.82 | EGFR (0.47) | EGFRKDRRETMAPTLCK | |
| SCHEMBL7914883 | 0.81 | MAPT (0.62) | KDRNPSR1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |