Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | PRNP | P04156 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PDE5A | O76074 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075273 | 0.82 | POLB (0.68) | MAPTPOLBPRNPRECQLABCG2 | |
| SCHEMBL3021512 | 0.82 | MAPT (0.81) | MAPTPOLBRECQLALDH1A1KDM4E | |
| SCHEMBL7914879 | 0.82 | EGFR (0.53) | MAPTPOLBPRNPRECQLALDH1A1 | |
| SCHEMBL7912132 | 0.82 | CA1 (0.69) | MAPTALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL3764417 | 0.81 | SHMT2 (0.60) | MAPTPOLBPRNPRECQLABCG2 | |
| SCHEMBL7904923 | 0.80 | MAPT (0.63) | MAPTPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL7918610 | 0.80 | MEN1 (0.56) | MAPTALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL8021598 | 0.78 | NPSR1 (0.79) | MAPTPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL2210475 | 0.78 | MAPT (0.56) | MAPTALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL7904940 | 0.77 | ENPP3 (0.70) | MAPTPOLBALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |