Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917172 | 0.79 | ADRB2 (0.57) | ADRB2ADRB1ADRB3LMNAMEN1 | |
| SCHEMBL28404335 | 0.77 | ADRB2 (0.78) | ADRB2ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL7441132 | 0.73 | LMNA (0.68) | ADRB2ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL14343723 | 0.72 | ADRB2 (0.65) | ADRB2ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL27182213 | 0.71 | ADRB2 (0.56) | ADRB2ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL28409380 | 0.71 | ADRB2 (0.80) | ADRB2ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL612864 | 0.70 | LMNA (0.75) | ADRB2ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL30781975 | 0.69 | ADRB2 (0.52) | ADRB2ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL28403894 | 0.69 | ADRB2 (0.78) | ADRB2ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL11862505 | 0.69 | ADRB2 (0.73) | ADRB2ADRB1ADRB3LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010061366-A1 | MANUFACTURE OF BISOPROLOL AND INTERMEDIATES THEREFOR | CORDEN PHARMA IP LIMITED (IE) | 2010-06-03 | — | — | WO | disclosed |