Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914960 | 0.79 | ADRB2 (0.51) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11222594 | 0.77 | ADRB2 (0.57) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11225356 | 0.77 | ADRB2 (0.57) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL8266174 | 0.73 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL7367812 | 0.73 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL25144632 | 0.73 | ADH1B (0.30) | — | |
| Hydrochloric Acid SCHEMBL10872169 | 0.72 | ADRB2 (0.97) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| Acetamide SCHEMBL5800005 | 0.70 | ADRB2 (0.83) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL10695011 | 0.69 | LMNA (0.44) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11667770 | 0.69 | ADRB2 (0.88) | ADRB2ADRB1CYP2D6ADRB3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010061366-A1 | MANUFACTURE OF BISOPROLOL AND INTERMEDIATES THEREFOR | CORDEN PHARMA IP LIMITED (IE) | 2010-06-03 | — | — | WO | disclosed |